To treat fungal infections of the skin of feet and hands, which are in most cases the source of infection for the nails, is used Lamisil cream, dermgel or spray. However, for the treatment of nails they are not effective.
Onychomycosis requires long-term treatment. The course of reception of tablets is generally from six weeks to six months. Duration of the course depends on the form of onychomycosis, the lesion and patient’s general condition. For example, in lesions of the nail plate brushes usually enough six weeks of treatment. A fungal nail infections of feet require three months of treatment. If the patient by nature has slow growing nails, three months is not enough, sometimes treatment is extended to six months. Lamisil action continues for several months after cessation of treatment, due to the regrowth of healthy nails.
Lamisil is effective against fungi-dermatophytes, which are the main causative agents of fungal nail infections.
When taking orally Lamisil accumulates in the nail plate in an amount sufficient to kill the pathogen. Active ingredient of Lamisil is terbinafine, inhibiting the action of certain enzymes of fungal cells, resulting in some cells a lack of excess and other biologically active substances. This leads to cell death of fungi.
Lamisil is not produced in the form of formulations for topical application for the treatment of onychomycosis.
Lamisil tablets for oral administration are generally well tolerated. But sometimes the side effects do happen, especially with prolonged use, which is required during onychomycosis. In such cases, symptoms such as discomfort and slight pain in the stomach, loss of appetite, nausea and sometimes (very rarely) vomiting, diarrhea, taste disturbance, liver dysfunction may occur only in the form of changes in laboratory parameters or in the form of jaundice and pain in the right subcostal area. Since disorders of the liver can occur before prescribing Lamisil check the function of this organ.